The 1st National Policy Forum for Science, Technology, and Innovation (STI) ended with calls for academia in Uganda to take lead in the STI ecosystem by identifying talent, knowledge management as well as creation of links with industry to support innovations. This is based on the effective models witnessed across the world as associated with the universities such as Harvard, MIT, and Stanford in the United States of America, and University of Cape Town in South Africa. It was reiterated that a better STI ecosystem will help catalyze national development for Uganda.